United States securities and exchange commission logo January 23, 2023 Jason DiBona Chief Executive Officer Molekule Group, Inc. 10455 Riverside Drive Palm Beach Gardens, FL 33410 Re: Molekule Group, Inc. Registration Statement on Form S-3 Filed January 13, 2023 File No. 333-269232 Dear Jason DiBona: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Kyle Wiley, Staff Attorney, at 202-344-5791 or Jan Woo, Legal Branch Chief, 202-551-3453 with any questions. Sincerely, Division of Corporation Finance Office of Technology cc: Valerie Jacob